Title : Similar maximum systemic but not local cyclooxygenase-2 inhibition by 50 mg lumiracoxib and 90 mg etoricoxib: a randomized controlled trial in healthy subjects.

Pub. Date : 2014 Jul

PMID : 24469906






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The local COX-2 inhibition by etoricoxib was most pronounced for PGD2. Etoricoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 CONCLUSIONS: Doses of 50 mg lumiracoxib and 90 mg etoricoxib produced similar maximum inhibition of systemic COX-2 function whereas 50 mg lumiracoxib was ineffective in producing local COX-2 inhibition. Etoricoxib mitochondrially encoded cytochrome c oxidase II Homo sapiens