Title : TP53 mutation-correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53-mutated breast cancers.

Pub. Date : 2014 May

PMID : 24462521






1 Functional Relationships(s)
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1 Consistent with the gene expression profiling and siRNA assays, the inhibition of MPS1 by SP600125 led to a reduction in cell viability and a significant increase in cell death, selectively in TP53-mutated BC cells. pyrazolanthrone TTK protein kinase Homo sapiens