Title : Discovery of AMG 232, a potent, selective, and orally bioavailable MDM2-p53 inhibitor in clinical development.

Pub. Date : 2014 Feb 27

PMID : 24456472






1 Functional Relationships(s)
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1 We recently reported the discovery of AM-8553 (1), a potent and selective piperidinone inhibitor of the MDM2-p53 interaction. 2-piperidone tumor protein p53 Homo sapiens