Title : αV β5 and CD44 are oxygen-regulated human embryonic stem cell attachment factors.

Pub. Date : 2013

PMID : 24455718






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Adhered hESCs following blockage of alphaV beta5 in 2% O2 displayed a reduction in nuclear colocalisation of Oct-4 and Nanog with little effect observed in 21% O2. Oxygen Nanog homeobox Homo sapiens
2 Blockage of CD44 had the converse effect with dramatic reductions in nuclear colocalisation of Oct-4 and Nanog in 21% O2 cultured hESC which retained adherence, but not in 2% O2 cultured cells. Oxygen Nanog homeobox Homo sapiens