Title : Activation of membrane estrogen receptors attenuates opioid receptor-like1 receptor-mediated antinociception via an ERK-dependent non-genomic mechanism.

Pub. Date : 2013

PMID : 24452062






1 Functional Relationships(s)
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1 E2BSA produced a parallel and significant increase in the phosphorylation of ERK 2 only in OVX females, and pre-treatment with MEK/ERK 1/2 inhibitor, U0126 (10 mug), blocked the mER-mediated abolition of ORL1-mediated antinociception in OVX females. U 0126 opioid related nociceptin receptor 1 Rattus norvegicus