Title : Reduction of the pro-inflammatory response by tetrandrine-loading poly(L-lactic acid) films in vitro and in vivo.

Pub. Date : 2014 Nov

PMID : 24442958






1 Functional Relationships(s)
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1 RAW 264.7 macrophages cultured in TET-loading PLLA films maintained lower levels of chemokines, cytokines, and enzymes involved in the inflammatory process, such as NO, TNF-alpha, IL-6, iNOS, COX-2 than control PLLA films, suggesting that TET-loading PLLA films could regulate the mRNA expression and protein expression to reduce the inflammatory response in macrophages. tetrandrine nitric oxide synthase 2 Rattus norvegicus