Pub. Date : 2015 Apr
PMID : 24436257
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arecoline-induced Egr-1 expression and its signaling pathways were assessed by Western blot analyses in human buccal mucosal fibroblasts (BMFs). | Arecoline | early growth response 1 | Homo sapiens |
| 2 | Arecoline, a main alkaloid found in the areca nut, stimulated Egr-1 synthesis in BMFs. | Arecoline | early growth response 1 | Homo sapiens |
| 3 | Pretreatment with antioxidant N-acetyl-L-cysteine, c-Jun NH2-terminal kinase inhibitor SP600125, and extracellular signal-regulated kinase inhibitor PD98059 significantly reduced arecoline-induced Egr-1 synthesis. | Arecoline | early growth response 1 | Homo sapiens |
| 4 | Epigallocatechin-3-gallate (EGCG) inhibited arecoline-induced Egr-1 synthesis and collagen gel contraction in a dose-responsive manner. | Arecoline | early growth response 1 | Homo sapiens |