Title : Human pyrroline-5-carboxylate reductase (PYCR1) acts on Δ(1)-piperideine-6-carboxylate generating L-pipecolic acid.

Pub. Date : 2014 May

PMID : 24431009






2 Functional Relationships(s)
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1 We here present evidence that PYCR1 is indeed able to produce L-pipecolic acid from P6C preparations, and the observed K m for this conversion is of the same magnitude as the K m described for the conversion of P5C to L-proline by PYCR1. Proline pyrroline-5-carboxylate reductase 1 Homo sapiens
2 We here present evidence that PYCR1 is indeed able to produce L-pipecolic acid from P6C preparations, and the observed K m for this conversion is of the same magnitude as the K m described for the conversion of P5C to L-proline by PYCR1. Proline pyrroline-5-carboxylate reductase 1 Homo sapiens