Pub. Date : 2014
PMID : 24422572
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The fact that the accumulation of metabolic substrates such as monosodium urate, ceramide, cholesterol, and glucose can trigger the NLRP3 inflammasome connects metabolic stress to IL-1beta-mediated inflammation and provides a rationale for therapeutically targeting IL-1 in prevalent diseases such as gout, diabetes mellitus, and coronary artery disease. | Glucose | NLR family pyrin domain containing 3 | Homo sapiens |