Pub. Date : 2014 Mar
PMID : 24421337
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress. | Flurbiprofen | leptin | Mus musculus |
| 2 | We demonstrated that flurbiprofen, a nonsteroidal anti-inflammatory drug (NSAID), exhibited chaperone activity, which reduced protein aggregation and alleviated ER stress-induced leptin resistance, characterized by insensitivity to the actions of the anti-obesity hormone leptin. | Flurbiprofen | leptin | Mus musculus |
| 3 | We demonstrated that flurbiprofen, a nonsteroidal anti-inflammatory drug (NSAID), exhibited chaperone activity, which reduced protein aggregation and alleviated ER stress-induced leptin resistance, characterized by insensitivity to the actions of the anti-obesity hormone leptin. | Flurbiprofen | leptin | Mus musculus |