Title : Tetraacylated lipid A and paclitaxel-selective activation of TLR4/MD-2 conferred through hydrophobic interactions.

Pub. Date : 2014 Feb 15

PMID : 24420921






1 Functional Relationships(s)
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1 The hexaacylated lipid A is an agonist of mouse (mTLR4) and human TLR4/MD-2, whereas the tetraacylated lipid IVa and paclitaxel activate only mTLR4/MD-2 and antagonize activation of the human receptor complex. Lipid A toll-like receptor 4 Mus musculus