Title : [2-deoxyglucose enhances chemosensitivity of androgen-independent prostate cancer cells to docetaxel].

Pub. Date : 2013 Oct 29

PMID : 24405548






5 Functional Relationships(s)
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1 OBJECTIVE: To explore the antitumor effects of 2-deoxyglucose (2-DG) plus docetaxel (Doc) on PC3 and DU145 cells and its mechanism. Docetaxel chromobox 8 Homo sapiens
2 OBJECTIVE: To explore the antitumor effects of 2-deoxyglucose (2-DG) plus docetaxel (Doc) on PC3 and DU145 cells and its mechanism. Docetaxel chromobox 8 Homo sapiens
3 The inhibition rates for PC3 proliferation at 48 h by Doc with concentrations of 0.1, 0.5, 2.5 nmol/L were 10.71%, 25.32% and 56.46% respectively. Docetaxel chromobox 8 Homo sapiens
4 The inhibition rates for PC3 cell proliferation by Doc plus 2-DG with a concentration of 1.0 g/L were 27.15%, 58.74% and 87.95% respectively and 29.53%, 59.41%, and 90.48% for DU145 respectively. Docetaxel chromobox 8 Homo sapiens
5 The apoptotic rates for PC3 and DU145 induced by Doc 0.5 nmol/L plus 2-DG 1.0 g/L at 48 h were 46.49% and 53.64% respectively. Docetaxel chromobox 8 Homo sapiens