Title : Regorafenib for treatment of advanced gastrointestinal stromal tumors.

Pub. Date : 2014 Mar

PMID : 24405315






2 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Regorafenib, a KIT/PDGFRA/vascular endothelial growth factor receptor (VEGFR) oral kinase inhibitor, has been shown to improve progression-free survival in the third- or fourth-line setting. regorafenib platelet derived growth factor receptor alpha Homo sapiens
2 Regorafenib activity in this setting is believed to be due to its activity against oncogenic forms of KIT/PDGFRA. regorafenib platelet derived growth factor receptor alpha Homo sapiens