Title : A novel immunomodulatory molecularly targeted strategy for refractory Hodgkin's lymphoma.

Pub. Date : 2014 Jan 15

PMID : 24395633






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1 Against this background, we report a dramatic response in a young patient with advanced HL refractory to the standard treatment who responded to the combination of a pan-histone deacetylase inhibitor (vorinostat, suberoylanilide hydroxamic acid, SAHA) and mammalian target of rapamycin (mTOR) inhibitor therapy (sirolimus,rapamume). Sirolimus histone deacetylase 9 Homo sapiens