Title : Release of arachidonic acid metabolites by human monocytes or lymphocytes: effect of treatment with interferon on stimulation by phorbol ester or calcium ionophore.

Pub. Date : 1987 Jul

PMID : 2439242






2 Functional Relationships(s)
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1 Pretreatment of monocytes with recombinant human interferon (IFN)-gamma or IFN-alpha for 18 hr resulted in enhanced release of labeled arachidonic acid and increased conversion to autocoids after TPA or ionophore stimulation. Arachidonic Acid interferon alpha 1 Homo sapiens
2 These results demonstrate the autocoid profile released by stimulated human monocytes and illustrate the effects of IFN treatment on the production of lipoxygenase metabolites of arachidonic acid as well as cyclooxygenase products. Arachidonic Acid interferon alpha 1 Homo sapiens