Pub. Date : 2013
PMID : 24392034
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arsenic trioxide overcomes rapamycin-induced feedback activation of AKT and ERK signaling to enhance the anti-tumor effects in breast cancer. | Arsenic Trioxide | AKT serine/threonine kinase 1 | Homo sapiens |
| 2 | Previously, we published that arsenic trioxide (ATO) inhibits AKT activity and in some cases, decreases AKT protein expression. | Arsenic Trioxide | AKT serine/threonine kinase 1 | Homo sapiens |
| 3 | Previously, we published that arsenic trioxide (ATO) inhibits AKT activity and in some cases, decreases AKT protein expression. | Arsenic Trioxide | AKT serine/threonine kinase 1 | Homo sapiens |
| 4 | Previously, we published that arsenic trioxide (ATO) inhibits AKT activity and in some cases, decreases AKT protein expression. | Arsenic Trioxide | AKT serine/threonine kinase 1 | Homo sapiens |
| 5 | Previously, we published that arsenic trioxide (ATO) inhibits AKT activity and in some cases, decreases AKT protein expression. | Arsenic Trioxide | AKT serine/threonine kinase 1 | Homo sapiens |
| 6 | Therefore, we propose that combining ATO and rapamycin may circumvent the AKT feedback loop and increase the anti-tumor effects. | Arsenic Trioxide | AKT serine/threonine kinase 1 | Homo sapiens |