Title : The attenuated inflammation of MPL is due to the lack of CD14-dependent tight dimerization of the TLR4/MD2 complex at the plasma membrane.

Pub. Date : 2014 Jun

PMID : 24380872






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 TLR4/MD-2 senses lipid A, activating the MyD88-signaling pathway on the plasma membrane and the TRIF-signaling pathway after CD14-mediated TLR4/MD-2 internalization into endosomes. Lipid A toll like receptor 4 Homo sapiens
2 TLR4/MD-2 senses lipid A, activating the MyD88-signaling pathway on the plasma membrane and the TRIF-signaling pathway after CD14-mediated TLR4/MD-2 internalization into endosomes. Lipid A toll like receptor 4 Homo sapiens