Title : Estradiol reduces ferrous citrate complex-induced NOS2 up-regulation in cerebral endothelial cells by interfering the nuclear factor kappa B transactivation through an estrogen receptor β-mediated pathway.

Pub. Date : 2013

PMID : 24376801






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1 Adding ferrous citrate (FC) complexes to the primary cultured mouse cerebral endothelial cells (CEC) to mimic the SAH conditions, we also showed that FC up-regulates NOS2 through nuclear translocation of NFkappaB induced by free radicals generation. Free Radicals nitric oxide synthase 2, inducible Mus musculus