Title : Polyoxygenated cholesterol ester hydroperoxide activates TLR4 and SYK dependent signaling in macrophages.

Pub. Date : 2013

PMID : 24376657






1 Functional Relationships(s)
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1 Using liquid chromatography - tandem mass spectrometry and biological assays, we identified an oxidized cholesteryl arachidonate with bicyclic endoperoxide and hydroperoxide groups (BEP-CE) as a specific OxCE that activates macrophages in a TLR4/MD-2-dependent manner. Hydrogen Peroxide toll like receptor 4 Homo sapiens