Pub. Date : 2013
PMID : 24376548
11 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Platelet content of nitric oxide synthase 3 phosphorylated at Serine 1177 is associated with the functional response of platelets to aspirin. | Aspirin | nitric oxide synthase 3 | Homo sapiens |
| 2 | Protein expression of nitric oxide synthase 3 (NOS3) was higher in ASA-sensitive than in ASA-resistant platelets but there were no differences in the platelet expression of nitric oxide synthase 2 (NOS2) isoform. | Aspirin | nitric oxide synthase 3 | Homo sapiens |
| 3 | Protein expression of nitric oxide synthase 3 (NOS3) was higher in ASA-sensitive than in ASA-resistant platelets but there were no differences in the platelet expression of nitric oxide synthase 2 (NOS2) isoform. | Aspirin | nitric oxide synthase 3 | Homo sapiens |
| 4 | Protein expression of nitric oxide synthase 3 (NOS3) was higher in ASA-sensitive than in ASA-resistant platelets but there were no differences in the platelet expression of nitric oxide synthase 2 (NOS2) isoform. | Aspirin | nitric oxide synthase 3 | Homo sapiens |
| 5 | Protein expression of nitric oxide synthase 3 (NOS3) was higher in ASA-sensitive than in ASA-resistant platelets but there were no differences in the platelet expression of nitric oxide synthase 2 (NOS2) isoform. | Aspirin | nitric oxide synthase 3 | Homo sapiens |
| 6 | The highest NOS3 expression in ASA-sensitive platelets was independent of the presence of T-to-C mutation at nucleotide position -786 (T(-786) C) in the NOS3-coding gene. | Aspirin | nitric oxide synthase 3 | Homo sapiens |
| 7 | However, platelet content of phosphorylated NOS3 at Serine (Ser)(1177), an active form of NOS3, was higher in ASA-sensitive than in ASA-resistant platelets. | Aspirin | nitric oxide synthase 3 | Homo sapiens |
| 8 | However, platelet content of phosphorylated NOS3 at Serine (Ser)(1177), an active form of NOS3, was higher in ASA-sensitive than in ASA-resistant platelets. | Aspirin | nitric oxide synthase 3 | Homo sapiens |
| 9 | However, platelet content of phosphorylated NOS3 at Serine (Ser)(1177), an active form of NOS3, was higher in ASA-sensitive than in ASA-resistant platelets. | Aspirin | nitric oxide synthase 3 | Homo sapiens |
| 10 | However, platelet content of phosphorylated NOS3 at Serine (Ser)(1177), an active form of NOS3, was higher in ASA-sensitive than in ASA-resistant platelets. | Aspirin | nitric oxide synthase 3 | Homo sapiens |
| 11 | CONCLUSIONS: Functional platelet responsiveness to ASA was associated with the platelet content of phosphorylated NOS3 at Ser(1177). | Aspirin | nitric oxide synthase 3 | Homo sapiens |