Title : A novel murine model of hypertrophic scarring using subcutaneous infusion of bleomycin.

Pub. Date : 2014 Jan

PMID : 24374669






1 Functional Relationships(s)
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1 CONCLUSIONS: The bleomycin infusion model stimulates dermal fibroproliferation, creating reproducible murine scars that are comparable to human hypertrophic scars in terms of histological features, collagen content and organization, cellularity, the presence of myofibroblasts, and expression of transforming growth factor beta1. Bleomycin transforming growth factor beta 1 Homo sapiens