Pub. Date : 2014 Mar
PMID : 24374093
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | GABA tea prevents cardiac fibrosis by attenuating TNF-alpha and Fas/FasL-mediated apoptosis in streptozotocin-induced diabetic rats. | gamma-Aminobutyric Acid | tumor necrosis factor | Rattus norvegicus |
| 2 | Further experiments showed that the STZ-induced protein levels of tumor necrosis factor-alpha (TNF-alpha), Fas, activated caspase-8 and caspase-3 were significantly inhibited by the GABA tea treatment. | gamma-Aminobutyric Acid | tumor necrosis factor | Rattus norvegicus |
| 3 | Further experiments showed that the STZ-induced protein levels of tumor necrosis factor-alpha (TNF-alpha), Fas, activated caspase-8 and caspase-3 were significantly inhibited by the GABA tea treatment. | gamma-Aminobutyric Acid | tumor necrosis factor | Rattus norvegicus |
| 4 | Therefore, our data suggest that the inhibiting effect of GABA tea on STZ-induced cardiac fibrosis in diabetic rats may be mediated by reducing blood glucose and further attenuating TNF-alpha expression and/or Fas/Fas ligand (FasL)-mediated apoptosis. | gamma-Aminobutyric Acid | tumor necrosis factor | Rattus norvegicus |