Title : Differential interactions of antiretroviral agents with LXR, ER and GR nuclear receptors: potential contributing factors to adverse events.

Pub. Date : 2014 Jan

PMID : 24372550






1 Functional Relationships(s)
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1 KEY RESULTS: Direct LBD interactions with LXRalpha and/or LXRbeta were predicted in silico and confirmed in vitro for darunavir, efavirenz, flavopiridol, maraviroc and tipranavir. Darunavir nuclear receptor subfamily 1 group H member 3 Homo sapiens