Title : Radioiodine therapy for castration-resistant prostate cancer following prostate-specific membrane antigen promoter-mediated transfer of the human sodium iodide symporter.

Pub. Date : 2014 Jan-Feb

PMID : 24369144






2 Functional Relationships(s)
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1 Radioiodine therapy, the most effective form of systemic radiotherapy available, is currently useful only for thyroid cancer because of the thyroid-specific expression of the human sodium iodide symporter (hNIS). Iodine-131 solute carrier family 5 member 5 Homo sapiens
2 These results show prostate-specific expression of the hNIS gene delivered by the PSMA promoter and effective radioiodine therapy of CRPC by the PSMA promoter-driven hNIS transfection. Iodine-131 solute carrier family 5 member 5 Homo sapiens