Title : Oxidation of carcinogenic benzo[a]pyrene by human and rat cytochrome P450 1A1 and its influencing by cytochrome b5 - a comparative study.

Pub. Date : 2013

PMID : 24362093






1 Functional Relationships(s)
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1 OBJECTIVES: Cytochrome P450 (CYP) 1A1 is the most important enzyme in both activation and detoxification of carcinogenic benzo[a]pyrene (BaP), in combination with microsomal epoxide hydrolase (mEH). Benzo(a)pyrene cytochrome P450 family 1 subfamily A member 1 Homo sapiens