Pub. Date : 2014 Feb 5
PMID : 24360935
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Instead, it reduced cAMP-activated chloride secretion and proliferation of MDCK cells in an AMP-activated protein kinase (AMPK)-dependent manner and had no effect on CFTR protein expression. | Cyclic AMP | protein kinase AMP-activated non-catalytic subunit beta 1 | Homo sapiens |
2 | Instead, it reduced cAMP-activated chloride secretion and proliferation of MDCK cells in an AMP-activated protein kinase (AMPK)-dependent manner and had no effect on CFTR protein expression. | Cyclic AMP | protein kinase AMP-activated non-catalytic subunit beta 1 | Homo sapiens |
3 | These results indicate that pranlukast retards renal epithelial cyst progression by inhibiting cAMP-activated chloride secretion and cell proliferation via CaMKKbeta-AMPK-mTOR pathway. | Cyclic AMP | protein kinase AMP-activated non-catalytic subunit beta 1 | Homo sapiens |