Pub. Date : 1987 Mar 25
PMID : 2435730
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Transcriptional regulation of the c-myc protooncogene by 1,25-dihydroxyvitamin D3 in HL-60 promyelocytic leukemia cells. | Calcitriol | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 2 | Exposure of HL-60 promyelocytic leukemia cells to calcitriol results in a decrease in steady-state levels of c-myc mRNA and induces cellular differentiation. | Calcitriol | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 3 | We have asked whether calcitriol has a direct effect on the transcription of the c-myc gene. | Calcitriol | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |
| 4 | We conclude that the effect of 1,25-(OH)2D3 on c-myc expression occurs at the transcriptional level. | Calcitriol | MYC proto-oncogene, bHLH transcription factor | Homo sapiens |