Title : In situ regulation of mammalian CTP synthetase by allosteric inhibition.

Pub. Date : 1987 Apr 15

PMID : 2435724






1 Functional Relationships(s)
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1 Measurements of [3H]uridine incorporation into cellular pyrimidine NTP pools as a function of time indicated that CTP synthesis in intact wild type cells was markedly inhibited in a cooperative fashion by small increases in CTP pools, whereas flux across the enzyme in mutant cells was much less affected by changes in CTP levels. [3h]uridine solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 Mus musculus