Title : A cascade leading to premature aging phenotypes including abnormal tumor profiles in Werner syndrome (review).

Pub. Date : 2014 Feb

PMID : 24356923






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The resultant p53 suppresses cell growth and induces a shorter cellular lifespan, and also compromises mitochondrial biogenesis leading to the overproduction of reactive oxygen species (ROS) causing multiple aging phenotypes. Reactive Oxygen Species tumor protein p53 Homo sapiens
2 The resultant p53 suppresses cell growth and induces a shorter cellular lifespan, and also compromises mitochondrial biogenesis leading to the overproduction of reactive oxygen species (ROS) causing multiple aging phenotypes. Reactive Oxygen Species tumor protein p53 Homo sapiens