Title : Gsta4 Null Mouse Embryonic Fibroblasts Exhibit Enhanced Sensitivity to Oxidants: Role of 4-Hydroxynonenal in Oxidant Toxicity.

Pub. Date : 2013 Jan 1

PMID : 24353929






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Treatment of Gsta4 null MEF with 1,1,4-tris(acetyloxy)-2(E)-nonene [4-HNE(Ac)3], a pro-drug form of 4-HNE, resulted in the activation and phosphorylation of the c-jun-N-terminal kinase (JNK), extracellular-signal-regulated kinases (ERK 1/2) and p38 mitogen activated protein kinases (p38 MAPK) accompanied by enhanced cleavage of caspase-3. 1,1,4-tris(acetyloxy)-2-nonene mitogen-activated protein kinase 3 Mus musculus