Title : Magnesium loss in cyclosporine-treated patients is related to renal epidermal growth factor downregulation.

Pub. Date : 2014 May

PMID : 24353324






4 Functional Relationships(s)
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1 Magnesium loss in cyclosporine-treated patients is related to renal epidermal growth factor downregulation. Magnesium epidermal growth factor Homo sapiens
2 We hypothesize that CsA-induced hypomagnesaemia is due to a renal magnesium leak, also in patients, resulting from a downregulation of the renal EGF production, thereby inhibiting the activation of TRPM6. Magnesium epidermal growth factor Homo sapiens
3 In the whole study population, log urinary EGF excretion is an independent predictor of the FE Mg(2+), supporting the role of EGF in magnesium reabsorption. Magnesium epidermal growth factor Homo sapiens
4 In the whole study population, log urinary EGF excretion is an independent predictor of the FE Mg(2+), supporting the role of EGF in magnesium reabsorption. Magnesium epidermal growth factor Homo sapiens