Pub. Date : 2014 Feb 7
PMID : 24352657
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have used an established cell-based assay employing a PC12 cell line overexpressing truncated exon 1 of Htt with a 103-residue polyQ expansion that yields polyQ-Htt aggregates to investigate the fate of polyQ-Htt-drug complexes. | polyglutamine | huntingtin | Rattus norvegicus |
| 2 | We have used an established cell-based assay employing a PC12 cell line overexpressing truncated exon 1 of Htt with a 103-residue polyQ expansion that yields polyQ-Htt aggregates to investigate the fate of polyQ-Htt-drug complexes. | polyglutamine | huntingtin | Rattus norvegicus |
| 3 | In light of these properties, we investigated the effect of scyllo-inositol on polyQ-Htt accumulation. | polyglutamine | huntingtin | Rattus norvegicus |