Title : A change in configuration of the calmodulin-KCNQ channel complex underlies Ca2+-dependent modulation of KCNQ channel activity.

Pub. Date : 2013

PMID : 24349250






1 Functional Relationships(s)
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1 These results suggest that a rise in intracellular calcium induces a change in the configuration of CaM-KCNQ binding, which leads to the reduction of KCNQ affinity for PIP2 and subsequent current suppression. Phosphatidylinositol 4,5-Diphosphate calmodulin 1 Homo sapiens