Title : Pharmacological targeting of p53 through RITA is an effective antitumoral strategy for malignant pleural mesothelioma.

Pub. Date : 2014

PMID : 24345738






1 Functional Relationships(s)
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1 Interestingly, we identified a previously undetected point mutation of p53 (p.Arg249Ser) in IST-MES 2, and showed that RITA is also able to reactivate this p53 mutant protein and its apoptotic function. 2-(N-morpholino)ethanesulfonic acid tumor protein p53 Homo sapiens