Title : The synthesis of novel taxoids for oral administration.

Pub. Date : 2014 Jan 1

PMID : 24332858






2 Functional Relationships(s)
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1 A group of novel taxoids, with modifications at C-7, C-10, C-3" and C-14 positions of paclitaxel, was synthesized in order to improve their biological profile by decreasing their affinity with P-glycoprotein (P-gp) and increasing cellular permeability. Taxoids ATP binding cassette subfamily B member 1 Homo sapiens
2 A group of novel taxoids, with modifications at C-7, C-10, C-3" and C-14 positions of paclitaxel, was synthesized in order to improve their biological profile by decreasing their affinity with P-glycoprotein (P-gp) and increasing cellular permeability. Taxoids ATP binding cassette subfamily B member 1 Homo sapiens