Title : Antigen-induced formation of a lymphokine with a possible role as a mediator of the late component of dual allergic reaction.

Pub. Date : 1987

PMID : 2433231






2 Functional Relationships(s)
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1 In a penicillin-allergic patient who showed a strong dual skin reaction (immediate and late components) to an intradermal injection of the antigen, we investigated the possibility that the lymphokine, histamine-releasing factor (HRF), which has been shown to release histamine from human basophils and mast cells, might play a part in the elicitation of the late phase of the "dual reaction". Histamine tumor protein, translationally-controlled 1 Homo sapiens
2 The purified HRF released histamine from the patient"s own leucocytes and also caused immediate wheal and flare reaction on intradermal injection. Histamine tumor protein, translationally-controlled 1 Homo sapiens