Pub. Date : 2014 Feb
PMID : 24326424
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Doxorubicin induced fibrosis (accumulated collagen deposition and increased CTGF), activated apoptosis (increased TUNEL index, apoptotic DNA fragmentation, and caspase-3 activity and decreased Bcl-2/Bax ratio), and suppressed phosphorylation status of prosurvival signals (ERK1/2 and Akt) in ventricular muscles. | Doxorubicin | mitogen-activated protein kinase 3 | Mus musculus |