Pub. Date : 2013 Sep
PMID : 24325097
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [Oxidative mechanism of uric acid induced CRP expression in human umbilical vein endothelial cells]. | Uric Acid | C-reactive protein | Homo sapiens |
| 2 | OBJECTIVE: To explore the oxidative mechanism of uric acid (UA) induced CRP expression in human umbilical vein endothelial cells. | Uric Acid | C-reactive protein | Homo sapiens |
| 3 | OBJECTIVE: To explore the oxidative mechanism of uric acid (UA) induced CRP expression in human umbilical vein endothelial cells. | Uric Acid | C-reactive protein | Homo sapiens |
| 4 | The effects of N-acetyl cysteine (NAC) on UA-induced levels of ROS, mRNA and protein of CRP in HUVECs were also observed. | Uric Acid | C-reactive protein | Homo sapiens |
| 5 | RESULTS: The results demonstrated that UA could significantly increase the mRNA and protein expression of CRP in HUVECs in time- and concentration-dependent manners. | Uric Acid | C-reactive protein | Homo sapiens |
| 6 | HUVECs were stimulated with 12 mg/dL UA at 6 h, mRNA and protein levels of CRP significantly higher than that of control level (P<0.05), reached a peak at 12 h (P<0. | Uric Acid | C-reactive protein | Homo sapiens |
| 7 | NAC reduced UA-induced levels of ROS, mRNA and protein of CRP in HUVECs compared with those of 12 mg/dL UA induced group(P<0. | Uric Acid | C-reactive protein | Homo sapiens |
| 8 | CONCLUSION: Uric acid significantly increased mRNA and protein expression of CRP in HUVECs in time- and concentration-dependent manners. | Uric Acid | C-reactive protein | Homo sapiens |