Pub. Date : 2014 Oct 1
PMID : 24321276
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Herein is presented the results of selective screening assays of a coumarin derivatives library using BChE and AChE covalently immobilized onto silica fused capillaries (ICERs, 15 cm x 0.1 mm ID). | coumarin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
| 2 | Two out of 20 coumarin derivatives could be highlighted: compound 17 is more active toward BChE (IC50=109 +- 21 muM) and 19 showed activity against both enzymes (BChE IC50=128 +- 28 muM and hu-AChE IC50=144 +- 40 muM). | coumarin | acetylcholinesterase (Cartwright blood group) | Homo sapiens |