Title : High glucose driven expression of pro-inflammatory cytokine and chemokine genes in lymphocytes: molecular mechanisms of IL-17 family gene expression.

Pub. Date : 2014 Mar

PMID : 24308966






1 Functional Relationships(s)
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1 High glucose induced gene profiling in Jurkat T-lymphocytes showed significantly increased expression of 64 proinflammatory genes including IL-6 and IL-17A and most of these genes were Nuclear Factor (NF)-kappaB and AP-1 regulated. Glucose interleukin 6 Homo sapiens