Pub. Date : 2014 Jun
PMID : 24307525
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mesenchymal stem/stromal cells inhibit the NLRP3 inflammasome by decreasing mitochondrial reactive oxygen species. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | Together, our results reveal that hMSCs inhibit NLRP3 inflammasome activation in macrophages primarily by secreting STC-1 in response to activated macrophages and thus by decreasing mitochondrial ROS. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |