Title : HMGB1 acts in synergy with lipopolysaccharide in activating rheumatoid synovial fibroblasts via p38 MAPK and NF-κB signaling pathways.

Pub. Date : 2013

PMID : 24302816






1 Functional Relationships(s)
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1 Furthermore, both NF- kappa B inhibitor Bay11-7085 and p38 inhibitor SB203580 significantly suppressed the enhanced production of IL-6 and MMPs induced by HMGB1-LPS. BAY 11-7085 interleukin 6 Homo sapiens