Title : Protective role of andrographolide in bleomycin-induced pulmonary fibrosis in mice.

Pub. Date : 2013 Dec 3

PMID : 24300094






4 Functional Relationships(s)
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1 Meanwhile, andrographolide significantly dose-dependently inhibited the ratio of phospho-NF-kappaB p65/total NF-kappaB p65 and NF-kappaB p65 DNA binding activities. andrographolide nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
2 Meanwhile, andrographolide significantly dose-dependently inhibited the ratio of phospho-NF-kappaB p65/total NF-kappaB p65 and NF-kappaB p65 DNA binding activities. andrographolide nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
3 Meanwhile, andrographolide significantly dose-dependently inhibited the ratio of phospho-NF-kappaB p65/total NF-kappaB p65 and NF-kappaB p65 DNA binding activities. andrographolide nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus
4 Our findings indicate that andrographolide compromised bleomycin-induced pulmonary inflammation and fibrosis possibly through inactivation of NF-kappaB. andrographolide nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus