Title : Tivozanib reverses multidrug resistance mediated by ABCB1 (P-glycoprotein) and ABCG2 (BCRP).

Pub. Date : 2014 Aug

PMID : 24295377






1 Functional Relationships(s)
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1 RESULTS: The results indicate that tivozanib can significantly reverse ABCB1-mediated resistance to paclitaxel, vinblastine and colchicine, as well as ABCG2-mediated resistance to mitoxantrone, SN-38 and doxorubicin. Colchicine ATP binding cassette subfamily B member 1 Homo sapiens