Pub. Date : 1986 Oct
PMID : 2428978
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | New effective gonadotropin releasing hormone antagonists with minimal potency for histamine release in vitro. | Histamine | gonadotropin releasing hormone 1 | Rattus norvegicus |
2 | In vitro: the affinity for the pituitary GnRH receptor was measured as was the ability of the analogues to inhibit GnRH-stimulated release of luteinizing hormone (LH) by dispersed anterior pituitary cells in culture and to release histamine from rat mast cells. | Histamine | gonadotropin releasing hormone 1 | Rattus norvegicus |
3 | Release of histamine was observed at doses 10-25 times that required for [Ac-D2Nal1,D4FPhe2,DTrp3,DArg6]-GnRH. | Histamine | gonadotropin releasing hormone 1 | Rattus norvegicus |