Pub. Date : 2014 Jan 24
PMID : 24287376
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We discovered that curcumin treatment could promote the number of processes, mean process length, and maximum process length of primary neurons, which were inhibited by reggie-1 siRNAs or extracellular signal-regulated kinase (ERK) 1/2 antagonist. | Curcumin | mitogen-activated protein kinase 3 | Homo sapiens |
2 | Furthermore, curcumin-induced neurite growth was related to the ERK1/2 phosphorylation, which was blocked by reggie-1 knockdown. | Curcumin | mitogen-activated protein kinase 3 | Homo sapiens |
3 | Overall, our results implied that curcumin could mediate neurite outgrowth through reggie-1 and ERK1/2 pathway. | Curcumin | mitogen-activated protein kinase 3 | Homo sapiens |