Title : β-Elemene, a compound derived from Rhizoma zedoariae, reverses multidrug resistance mediated by the ABCB1 transporter.

Pub. Date : 2014 Feb

PMID : 24284783






2 Functional Relationships(s)
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1 Finally, beta-elemene at 100 microM partially (~50%) increased the sensitivity of the BCRP-overexpressing cell line, NCI-H460/MX20, to mitoxantrone, but beta-elemene did not significantly alter the resistance of MRP1-transfected HEK293/MRP1 cells to vincristine. beta-elemene ATP binding cassette subfamily C member 1 Homo sapiens
2 Finally, beta-elemene at 100 microM partially (~50%) increased the sensitivity of the BCRP-overexpressing cell line, NCI-H460/MX20, to mitoxantrone, but beta-elemene did not significantly alter the resistance of MRP1-transfected HEK293/MRP1 cells to vincristine. beta-elemene ATP binding cassette subfamily C member 1 Homo sapiens