Title : Role of amino acid transporters in amino acid sensing.

Pub. Date : 2014 Jan

PMID : 24284439






1 Functional Relationships(s)
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1 AA transporters at the cell surface, particularly those for large neutral AAs such as leucine, interact functionally with intracellular nutrient-signaling pathways that regulate metabolism: for example, the mammalian target of rapamycin complex 1 (mTORC1) pathway, which promotes cell growth, and the general control non-derepressible (GCN) pathway, which is activated by AA starvation. Leucine CREB regulated transcription coactivator 1 Mus musculus