Pub. Date : 2014 Jun
PMID : 24277525
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Chronic nicotine treatment reverses hypothyroidism-induced impairment of L-LTP induction phase: critical role of CREB. | Nicotine | cAMP responsive element binding protein 1 | Rattus norvegicus |
| 2 | Five minutes after MHFS, Western blotting showed an increase in the levels of P-CREB, and P-MAPKp42/44 in sham-operated control, nicotine, and nicotine-treated hypothyroid animals, but not in hypothyroid animals. | Nicotine | cAMP responsive element binding protein 1 | Rattus norvegicus |
| 3 | Therefore, normalized phosphorylation of essential kinases such as P-CREB and P-MAPK p42/44 in the CA1 area of nicotine-treated hypothyroid animals plays a crucial role in nicotine-induced rescue of L-LTP induction during hypothyroidism. | Nicotine | cAMP responsive element binding protein 1 | Rattus norvegicus |
| 4 | Therefore, normalized phosphorylation of essential kinases such as P-CREB and P-MAPK p42/44 in the CA1 area of nicotine-treated hypothyroid animals plays a crucial role in nicotine-induced rescue of L-LTP induction during hypothyroidism. | Nicotine | cAMP responsive element binding protein 1 | Rattus norvegicus |