Title : Synergistic cooperation between sunitinib and cisplatin promotes apoptotic cell death in human medullary thyroid cancer.

Pub. Date : 2014 Feb

PMID : 24276455






2 Functional Relationships(s)
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1 RESULTS: Sunitinib and cisplatin synergistically inhibited the growth of MZ-CRC-1 cells harboring the RET M918T activating mutation. Sunitinib ret proto-oncogene Homo sapiens
2 CONCLUSIONS: Addition of cisplatin to sunitinib potentiates apoptotic cell death and has promising preclinical activity in MTCs harboring the RET M918T oncogene. Sunitinib ret proto-oncogene Homo sapiens